BLIS K12, an anti-bacterial “bullet”

BLIS K12, a super powerful oral probiotic

oral probiotics, BLIS K12, anti-bacterial, natural cold remedyA patented strain of oral probiotics, known as Streptococcus salivarius K12, is a naturally occurring bacteria found in a very small percentage of the human population (2% or less of people have this bacteria in their mouths).

Scientists discovered BLIS K12 by studying people that were unusually free of illness, particularly oral ailments.

These people almost never got ill with sore throats or colds and had few oral ailments, including a low incidence of bad breath, halitosis. Further study showed that these individual’s mouths were naturally populated with a powerfully beneficial bacterial strain, now called BLIS K12.

This was a finding that was of great interest due to its potential for naturally boosting immunity and oral health, so further studies followed. Researchers were particularly interested in how this strain was able to provide such beneficial results, what was the mechanism behind it all?

Well these smart researchers did figure it out and a simplified explanation is given below, but first let’s define a couple terms:

BLIS: an abbreviation that stands for Bacteriocin like Inhibitory Substance (Bacteriocin is a compound word that means a toxin produced by one bacteria that is harmful or lethal to other bacteria).

Peptide: in very simple terms these are just groups of amino acids, proteins, that are bonded together. Basically a compound of amino acids.

OK, still with us? Good, because here is where it gets interesting.

This bacterial strain (S. salivarius K12) actually creates a couple peptides that are like bullets fired against incoming invader bacteria! It is quite clever, the BLIS K12 is actually able to recognize the other bacteria, target it and fire away with these peptide “bullets”. Just like being shot by a gun, these peptide “bullets” (technically they are called BLIS) pop a hole in the invading bacteria cell wall, and then these bacteria effectively bleed to death.

The BLIS K12 (K12 is just a random name given to this strain) bacteria are like roving immune squads, firing away at the “bad” bacteria that cause many types of ear-nose-throat infections as well as oral health ailments such as bad breath, gum disease and plaque formation.

Fantastic news, except if you are one of the 98% of humans that do not naturally possess this bacteria! Thankfully one can supplement with quality oral probiotics and populate your mouth–thus obtaining these great benefits.

But it is important to remember that BLIS K12 is not a drug but a living bacteria.

Why is this important? Well, it means that one is dealing with living entities and certain lifestyle habits, smoking and drinking in particular, can make it very, very difficult for the BLIS K12 to survive. In addition, the use of heavy chemicals and antibacterial oral products will also work against these beneficial bacteria, as they don’t just target and kill off the “bad” bacteria.

There is another important factor to consider in choosing an oral probiotic product. The oral probiotics have to be effective at the job of integration and adhesion into the oral biofilm (think of “biofilm” as a living, bacterial colony that coats, like a film, your mouth and teeth). Biofilms are like exclusive neighborhoods, they can be hard to get into and resist newcomers! If the oral probiotics can’t get into the “neighborhood” then they can’t go to work.

A quality oral probiotic, such as our Advanced Oral Probiotic Blend from Great Oral Health, is compounded with oral probiotics that have a proven capacity for working their way into the biofilms and extant bacterial colonies in your mouth. In addition, we manufacture our oral probiotics with proprietary ingredients designed to boost the chalky texture which boosts our adhesion factor tremendously.

Keep in mind that while it can take weeks, if not months, to see full results from any probiotic regimen, studies have shown significant results within weeks of taking BLIS K12.

Clinical studies have shown significant results in reducing illness, boosting gum health, improving bad breath and a number of other symptoms associated with the regular use of oral probiotics.

Find out more on our website:

Do you see yourself in any of these videos?

If this seems familiar you better order a bottle today!

Watch some funny Bad Breath videos from Vine and YouTube

Two more classic sketches. Meet Bernard Pearson, a man with really bad breath. And Billy visits Johnny in hospital. I wonder if you can guess what operation he’s had

Bad Breath? How Probiotics Can Help

Excellent reading on how Probiotics help with bad breath found on Huffington Post


Bad Breath? How Probiotics Can Help

If you’re staying on top of the world of health products, you already know about probiotics. Different from antibiotics, probiotics are a natural way to help your body defend against outside predators. May sound a bit militaristic, but actually probiotics are about trumping bad bacteria with the good. If you’ve missed the probiotic boat, fear not! You can start now and never be behind. Here are some noteworthy mentions of probiotics to get you up to speed.

There are many ways to freshen one’s breath, from odor-neutralizing tablets to oral rinses. One of the most cutting-edge methods of stopping halitosis is oral care probiotics, according to one article. First, some basics: A lot of mouth odor comes from way further down the gastrointestinal (GI) track, and is caused by how the bacteria that inhabit your GI track metabolize the food you send down there. So changing your bacteria can often change the odors from your mouth.

couple, hugging, smiling, fresh breath

Oral care probiotics is a system of bacterial replacement that may be quite effective in stopping oral odor. A study published in the journal Current Opinion in Gastroenterology echoes this idea. This study was conducted as a review of the advances probiotics have made in the previous year. Results proclaim that this was a great year for probiotics because of products such as oral care probiotics that can be used to treat numerous conditions, halitosis being one of them. Probiotics can help replace the odor-causing oral bacteria with other harmless ones.

Basically, oral probiotics contain “good” bacteria that replace or eliminate “bad” bacteria in the body. Recently, there has been an oral care probiotic that will actually benefit the oral cavity itself. How did probiotics come to be?

According to the journal Communicating Current Research and Educational Topics and Trends in Applied Microbiology, Nobelist and Ukrainian scientist Elie Metchnikoff first discovered probiotics in 1907. Metchnikoff posited that flora growing in the stomach and intestine could be changed by replacing them with new bacteria. He also hypothesized that bacteria within the gut caused aging. He coined the term “gerontology,” meaning the study of longevity. This idea has been disproven, but his other probiotic theory has caught wind. It is possible that ingesting milk or yogurt might change the bacteria composition in the gastrointestinal tract.

Studies have also indicated that oral health can be improved through the use of oral care probiotics — more research is still being done, but there have been great advances made. The European Journal of Pediatrics published a study in 2001 that discusses finding the use of a harmless strain of Escherichia coli (E. coli) greatly improved bad breath that came from gastric gases. Yet another, more recent study in the journal Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology showed that Lactobacillus salivarius may combat bad breath coming from the mouth. In this study, Japanese researchers gave subjects with halitosis low amounts of L. salivarius and found that after a month, participants’ oral levels of sulfur-producing compounds had significantly decreased. The Journal of Applied Microbiology also published a study that found a week-long course of L. salivarius dramatically dropped the amount of volatile sulfur compounds in the oral cavity.

As noted in an article, a study in the International Journal of Contemporary Dentistry noted that adding Streptococcus salivarius bacteria into the mouth after rinsing with mouthwash can reduce levels of sulfur on one’s breath — meaning less bad breath. Researchers stated oral care probiotics are able to reduce halitosis by muscling out harmful (and halitosis-producing) bacteria with strains that will not produce oral odors. Other noteworthy applications of beneficial bacteria strains can help the body’s resistance to (and may reduce occurrences) of gum disease, cavities, sore throats and more.

Another article notes the ever-increasing amount of positive studies being published for oral care probiotics. A Swedish study found that the probiotic bacteria Lactobacillus may have many benefits for users’ oral health. These beneficial bugs might combat many harmful bacteria that cause the most severe dental problems. Unfortunately, only a small amount of people have active amounts of these microbes naturally in their mouths. Studies done in the 1960s initially showed that 30 to 40 percent of people had Lactobacillus. However, a current study found that this number has sharply decreased to a mere 10 to 20 percent of people. What brought this drastic change? Researchers say it may be due to diet.

Gabriela Sinkiewicz, a Malmo University researcher that led this recent study believes that people don’t eat as much fermented food (such as sauerkraut) and we use preservatives that kill bacteria in both the body and the food we consume. By introducing probiotics into the mouth, we may be able to fight off more harmful bacteria and stop them from infecting our mouths. So if your diet is full of preservatives, perhaps taking an oral care probiotic would be a good choice. Given the rise in probiotics, there is a variety to choose from. As stated earlier, there are now even oral care products that contain probiotics.

While tons of studies are continuing to be done, the articles above do point out the found benefits of using oral probiotics. It may seem like a lot of science, but the basic notion is simple: Beneficial bacteria found in probiotics can replace existing harmful ones. Perhaps probiotics are worth trying the next time you’re looking for a fresh breath solution.


Original Article can be found here.


To Beat Bad Breath, Keep the Bacteria in Your Mouth Happy Curing halitosis requires the right balance of oral microbes


Fantastic Article from Scientific America on Probiotics to helping to create a healthy mouth!

To Beat Bad Breath, Keep the Bacteria in Your Mouth Happy
Curing halitosis requires the right balance of oral microbes

Apr 16, 2013 |By Deborah Franklin


Most adults have bad breath occasionally, particularly when their mouth dries out after, say, a full night’s sleep or a long, dehydrating plane flight. About 25 percent of people worldwide, however, have chronic foul breath. Researchers around the world figured out years ago that gas-emitting bacteria on the tongue and below the gum line are largely responsible for rotten breath. But determining how best to eradicate these microbes’ tenacious odors has been difficult.

Solutions to date offer only temporary relief. Even scrupulously skipping onions and garlic, swishing mouthwash after every meal, mouth_and_bacteriaand brushing and flossing one’s teeth until they gleam like pearls will probably not sweeten a case of stubbornly stinky breath. Lightly scraping away any coating on the tongue can greatly improve the fragrance of one’s breath for at least a few hours. Certain bacteria-slaying mouthwashes provide short-term freshness, too, although many produce unpleasant side effects, such as a tingling sensation in the mouth. Lately some scientists have developed innovative mouth rinses that neutralize the rancid compounds produced by bacteria.

Recent evidence from international research suggests, however, that the most effective strategy for beating back bad breath may be more about nurturing helpful bacteria in the mouth than about destroying the offending germs and their by-products. Instead of singling out ostensible culprits, microbiologists are now shifting their focus to entire communities of microbes on the tongue, gum and teeth to figure out why some people have a sweeter-smelling oral village than others.

Breath’s Chemical Code
Bad breath has, of course, plagued humans for ages. Young girls, Hippocrates advised, should regularly rinse their mouths with wine, anise and dill seed. By the early 1970s Joseph Tonzetich of the University of British Columbia had begun to tackle the problem with technology. He used his lab’s gas chromatograph, a machine that separates a complex gaseous bouquet into its constituent compounds, to tease out reeking breath’s signature chemicals.

Sulfur compounds that easily vaporize were among the stinkiest chemicals Tonzetich identified in bad breath, especially hydrogen sulfide, which smells like rotten eggs, and methyl mercaptan, which smells like rotten cabbage. Since then, scientists have detected around 150 molecular components of human exhalations, many of them putrid. Dimethyl sulfide (think rotten seaweed) and the tellingly named cadaverine, putrescine and skatole are just a few such pungent molecules. Still, hydrogen sulfide and methyl mercaptan stand out: in study after study, the higher the levels of these two molecules in breath, the more that breath offends the human nose.

These smelly compounds are waste products released by the millions of bacteria feasting on particles of food and tissue in our mouth. Above the gum line, gram-positive species, which have relatively simple cell walls, dominate dental plaque—the living film of bacteria coating teeth. Streptococcus mutans and other sugar-loving gram-positives spew acid and dissolve enamel but are not heavy producers of foul-smelling compounds. In contrast, gram-negative bacteria—which have an extra cell wall layer—live mostly below the gum line and are much gassier. Some of these resilient bacteria, including Porphyromonas gingivalis, Treponema denticola and Prevotella intermedia, thrive in gaps between the gum and tooth and in the mosh pit crevices of the tongue.

Bacterial Colleagues
Gram-negative bacteria on the tongue may produce most of the foul odors in breath, but recent research emphasizes that no single type of oral bacterium creates bad breath on its own. Mel Rosenberg, an emeritus professor of microbiology at Tel Aviv University, and his colleague Nir Sterer recently found, for example, that some strains of gram-positive bacteria secrete an enzyme that clips sugar molecules off the proteins found in food, which in turn makes those proteins more digestible for nearby gram-negative organisms. The more proteins the gram-negatives digest, the more odors they emit.

Such interactions illustrate why researchers are increasingly interested in oral ecology, viewing the mouth as a kind of densely populated tide pool. Fresh breath reflects a healthy mouth, which is not necessarily one that lacks “bad” bacteria, scientists are realizing, but rather one in which overlapping bacterial colonies hold one another in check.

Bacterial geneticists contributing to the Human Microbiome Project, funded by the National Institutes of Health, have so far identified about 1,000 species of bacteria that commonly inhabit human mouths. Yet one person’s particular mix of “bacterial colleagues,” as Rosenberg calls them, is probably quite different from another’s. “Each person has maybe 100 to 200 of those bacterial species colonizing their mouth at any given time,” says Wenyuan Shi, a microbiologist at the University of California, Los Angeles.

During birth our previously sterile mouth picks up some of our mother’s bacteria, and in childhood we quickly acquire new microbial colonizers. Studies suggest that a preschooler’s population of mouth microbes most closely mimics his or her primary caregiver’s. As the years go on, diet, stress, illness, antibiotics and other forces can shift the demographics of an individual’s microbial community—and change its collective aroma. When bacteria that release smelly compounds dominate, chronic bad breath may be one of the consequences.

Many current treatments do not improve oral ecology—in fact, they might make matters worse. Although some mouthwashes merely mask unpleasant odors, alcohol-based rinses sold in drugstores and prescription rinses containing chlorhexidine or other antiseptics target all oral bacteria, stinky and otherwise. Shi says that approach has several drawbacks. A chlorhexidine rinse, for example, may improve breath for as long as 24 hours but can temporarily change the taste of food. In one study, 25 percent of subjects experienced a tingling or burning sensation on the tongue after a week of use. Heavy use of rinses with alcohol can dry out the mouth, sometimes exacerbating bad breath. Further, wiping out too many of the mouth’s native bacteria could disrupt the usual checks and balances, making way for opportunistic species responsible for gum disease and other infections to move in and take over.

A number of researchers are now working on promising alternatives to basically carpet bombing all oral bacteria. Some new mouthwashes go after the stink rather than the stinkers with ions of zinc or other metals that bind and neutralize sulfur compounds. Rosenberg, who started his career as a petroleum microbiologist, has developed a two-phase oil-and-water rinse that temporarily reduces bad breath by sopping up some of the oral debris and microbes that toothbrushing, flossing and tongue scraping miss.

Other teams are investigating whether probiotics rife with a gram-positive bacterial strain known as Streptococcus salivarius K12 can fight halitosis. A common resident of the mouth and respiratory tract, S. salivarius K12 is benign and known to produce substances that deter harmful bacteria. In a recent study by researchers in New Zealand and Australia, volunteers gargled with a chlorhexidine mouthwash to clear their palate of many native bacteria and subsequently sucked on lozenges laced with K12. Seven and 14 days later they had much sweeter breath. Presumably K12 outcompeted its foul-smelling kin, opening up niches for less offensive species.

At U.C.L.A., Shi and his team are working on a mouthwash that contains a peptide—a chain of amino acids smaller than a protein—tailored to selectively kill S. mutans, the ringleader behind tooth decay. Researchers could develop an analogous peptide to weed out the bacteria behind bad breath, Shi says. A rinse containing such peptides might free up real estate on the tongue for less malodorous microbes, if used in moderation. Rinsing every day risks a sudden and drastic shift in oral ecology that could have unexpected repercussions.

Shi himself brushes and flosses daily but does not use a mouthwash or even a tongue scraper because his family assures him that his breath smells fresh. “I’m one of the lucky ones,” he says. “My goal is to help other people be lucky, too.”

Common Scents
Researchers have identified around 150 different molecules in human breath, many of which offend the human nose. Here are what some of the more malodorous compounds smell like.

Rotten eggs
Hydrogen sulfide (H2S)

Rotten cabbage
Methyl mercaptan (CH3SH)

Allyl mercaptan (C3H6S)
Allyl methyl sulfide (C4H8S)

Dimethylamine (C2H7N)
Trimethylamine (C3H9N)

How to Beat Bad Breath

To Beat Bad Breath, Let Oral Probiotics Lead the Fight

mature woman, fresh breath, kiss, smiling.

Most adults will experience bad breath at some time in their lifetime. This is more likely to happen when their mouth dries out after a full night’s sleep or after a long trip on a plane. But for many this malady is not a temporary dilemma.

“About 25 percent of people worldwide, however, have chronic foul breath. Take your bad breath away_stinkbombResearchers around the world figured out years ago that gas-emitting bacteria on the tongue and below the gum line are largely responsible for rotten breath. But determining how best to eradicate these microbes’ tenacious odors has been difficult.” – Scientific American

Moreover, some have to come to discover that traditional bad breath solutions have only offered temporary relief. Using mouthwash after every meal and brushing, and flossing one’s teeth until they glisten like diamonds, will not address a case of stubborn halitosis. Other solutions have included scraping away any coating on the tongue, of which can improve the heinous nature of one’s breath for a couple of hours.

Recent evidence from international research suggests that the most effective strategy for beating back bad breath may be more about nurturing helpful bacteria in the mouth than about destroying nasty germs. Instead of singling out the evil sources of bad breath, microbiologists are now moving their focus to entire communities of microbes on the tongue, gum and teeth to figure out why some people have a better breath.

Introducing a Scientific Blend of Oral Probiotics

Great Oral Health now offers an oral probitotics product whose aim is to fight bad breath with providing a positive solution to the primary source of chronic bad breath: “Volatile Sulfur Compounds” (VSC) produced by bacteria.

“By controlling these bacteria, we would be providing an effective and scientific-based solution to this age old problem of bad breath”, states founder, Dr. Paul O’Malley, DDS.

Clinical tests have supported this logic. One such test, using a lozenge containing S. Salivaius K-12 (one of our ingredients) showed that this probiotic strain could significantly reduce VSC levels in 85% of the test subjects–quite impressive.

Several means by which probiotics work to control bad breath:

  • One, the probiotics compete with the existing bad bacteria and reduce their presence by “crowding them out”
  • Two, the probiotics produce BLIS or “bacteriocin-like-inhibitory-substances” which is a technical way of stating that a probiotic (bacteria) can produce substances that inhibit or kill other bacteria.
  • Three, by working to control gingivitis, gum disease and tooth decay these probiotics reduce the very sources of bacteria-generated odors in the mouth.

To find out more about Great Oral Health’s oral probiotics, visit

Oral Probiotics to Complete Probiotic Coverage

Oral probiotics may be the stuff of miracles, when it comes to total family oral care and the prevention of cavities, gum disease, and bad breath. It may also prevent the precipitation and severity of ear,nose, and throat infections.
Thankfully,People are becoming more aware of alternative healthcare options, especially in the realm of prevention.

Right now there are more than 4 Billion people world wide who have extensive gum disease and/ or cavities. We can put people in outer space, create intricate robotics, and computers, yet the epidemic of cavities and gum disease persist.

It is my opinion that the old model of trying to brush and swish and kill germs is only one side of the formula to eradicate these diseases. You see the bacteria that live in our mouth ,tongue,sinus and throat repopulate every 4-6 hours no matter how hard we kill them.

However, if we can eradicate them and add back the good ones they should inhibit and suppress the bad bugs from returning and taking hold.

This is in fact what happens when this approach is consistently applied.

I founded the company Great Oral Health to really help revolutionize the oral care industry. Our first product is the worlds most advanced and potent oral probiotic. This probiotic for the mouth is the simplest, fastest way to re-populate the oral environment with naturally occurring healthy bacteria.

My 7 strain formula will quickly bring balance and harmony to the good and bad bacteria with the former defeating the later. Guaranteed 3 billion at manufacture and 1 billion til expiration by using the patented livebac technology allows us to deliver whats promised with consistency.

Of course one should still brush,floss, and tongue scrape, but with my great tasting chewable oral probiotics the real miracles will occur!!!

Like what? Noticeably Fresher healthier breath,teeth, and gums. Less plaque and less inflamed gums if present. Some studies show that the bacteria that cause cavities,gum disease,and bad breath may be reduced by 80%!!

This is the most preventive formula I know of to date, so please don’t miss out on this first ever natural way to protect you and your family from the needless sufferings associated with gum disease, cavities and the embarrassment of bad breath.

Literally wake up feeling more refreshed as regards your breath and the taste and build up in your mouth, for now they are handled so easily and fast.
Please visit great oral for more info and how to get your probiotic for the mouth to protect yourself and your family. It is time to put this epidemic to rest!!!!

Paul O’Malley DDS,FIADFE

Wake Up with a Fresh and Clean Feeling

Our Oral Probiotics Hit BAD BREATH at Its Source-Bacterial Overgrowth

Practically one-for-one the feedback and testimonials from our happy users all share that fact that their mouths feel fresher and cleaner when they wake up. That slimy and stale morning feeling went away, leaving a cleaner, fresher and brighter start to the day.

Our oral probiotics are designed to work their way into the bacterial colonies that generate that rotten-egg, sulfur smell. As our beneficial bacteria colonizes it both crowds out and kills off the “bad” bacteria, helping you to experience fresher, healthier breath.

Great Oral Health for the Entire Family

Now have great oral health for everyone you love.

Clinical studies have shown the significant improvement in gum health as well as cavity reduction by the regular use of Oral ProBiotics.

Our Advanced Oral Probiotics formulation can help your entire family enjoy better health and happier smiles. With 7 powerful strains of beneficial bacteria, chosen specifically by our Holistic Dentist Founder, these are built for results.

Revolutionary Oral Health Products for YOU and Your FAMILY!

Our mission, from the very first spark, was to bring healthy, innovative and natural products to individuals across the world with the aim of changing the very face of oral health.