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Nano Hydroxyapatite (NHA) vs. Fluoride

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Time to read 7 min

When it comes to preventing dental decay, fluoride has long been the accepted standard in oral health. However, nano hydroxyapatite is quickly gaining a presence and reputation as a natural and effective treatment alternative.


Both substances aim to protect teeth by remineralizing enamel and preventing cavities, but they do so in distinct ways with differing implications for health and safety.

How Fluoride Works


Fluoride works by integrating into the tooth enamel and making it more resistant to acid attacks from bacteria in the mouth. In simple terms, the fluoride binds to the enamel and then attracts calcium. Together they then form a hardened protective layer in your enamel. Fluoride, by itself, does not remineralize. It only acts to attract calcium which, together, forms a compound called fluorapatite.


This process alters the chemical structure of the enamel, creating a harder surface that is less soluble and more resistant to decay. While effective, this method doesn't restore the enamel's natural composition; instead, it creates a stronger but more brittle material, which can sometimes lead to other dental issues like fluorosis (the appearance of discoloration, such as faint white lines or streaks on the teeth, that only occurs when one consumes too much fluoride).

toothbrush with fluoride toothpaste
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Nano Hydroxyapatite’s Natural Approach


Nano hydroxyapatite's role in oral care is a perfect example of biomimicry, where science follows and duplicates nature's strategies to solve human problems. The natural approach of nano hydroxyapatite is based on its similarity to the calcium mineral found in human bone and tooth enamel–hydroxyapatite. This biocompatibility is a cornerstone of its effectiveness and safety.

The Composition of Nano Hydroxyapatite


To fully appreciate nano hydroxyapatite's natural approach, it's important to understand its composition. Hydroxyapatite is a naturally occurring mineral form of calcium, containing calcium, phosphorus, and hydroxide ions. In nano hydroxyapatite, these particles are engineered to nanometer (think super tiny) dimensions. This process is what allows and encourages the process of absorption into your tooth enamel. It mimics the natural process that nature evolve over eons to keep your teeth strong and healthy.

How Nano Hydroxyapatite Replicates Natural Enamel


When nano hydroxyapatite is applied to teeth, it naturally bonds with the hydroxyapatite already present in the enamel. This process essentially "fills in" the microscopic gaps and scratches that have occurred due to everyday wear and tear, acidic reactions, or dietary impacts. Because it's structurally similar to the original enamel, the repair process maintains the natural characteristics of the teeth, preserving their translucency and strength.


This ability to integrate and repair is in stark contrast to treatments that layer foreign materials over the tooth surface, potentially altering its natural properties. Instead, nano hydroxyapatite rebuilds the enamel in a way that genuinely restores its original integrity.

Woman with sensitive teeth
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enamel repair on tooth
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Benefits of Nano Hydroxyapatite's Natural Healing Process


  1. Enhanced Remineralization: Nano hydroxyapatite not only covers surface imperfections but also penetrates deeper into the initial layers of the enamel. This penetration enables a deeper remineralization, which is more effective than topical treatments that only address surface-level decay. As a result, NHA is highly effective at relieving sensitivity issues.
  2. Prevention of Demineralization: By replicating and reinforcing the natural enamel structure, nano hydroxyapatite provides a robust defense against future demineralization. It creates a barrier that is less susceptible to acidic environments, a common cause of enamel erosion.
  3. Preservation of Natural Tooth Appearance: Since nano hydroxyapatite maintains the natural appearance of teeth, it avoids the pitfalls of cosmetic treatments that can sometimes give teeth an unnaturally opaque or matte finish. Teeth repaired with nano hydroxyapatite retain their natural luster, blending seamlessly with untreated areas. As an added benefit, as NHA is a pure white crystal, this adds a natural whitening effect to your enamel.

Long-Term Oral Health Benefits


For oral health support, nano hydroxyapatite not only focuses on immediate repair and protection but also promotes long-term oral health. By maintaining the natural structure and health of the enamel, it helps ensure the longevity of teeth, preventing conditions like cavities and sensitivity that can lead to more serious dental procedures.


Moreover, nano hydroxyapatite is free from the controversies and potential health concerns associated with synthetic chemicals and treatments. Its non-toxic nature makes it a safe option for all ages, supporting dental health from early childhood through to old age.

Fluoride’s Toxicity Concerns


One of the most significant differences between nano hydroxyapatite and fluoride is their safety profiles. Fluoride, while generally safe in small amounts, can be toxic at higher doses. Acute fluoride toxicity can occur from ingesting large amounts of fluoride in a short period, which can lead to symptoms like gastrointestinal discomfort, pain, nausea, and in severe cases, even death.


Chronic fluoride exposure, even at lower levels, can also have adverse effects. Dental fluorosis causes discoloration and pitting of the teeth, occurring when young children consume too much fluoride while their teeth are still developing. Skeletal fluorosis, another serious condition, results from long-term exposure to high levels of fluoride and can cause pain and damage to bones and joints.


Moreover, concerns have been raised about the potential link between fluoride and various health issues, including neurological problems and lower IQ scores in children. While definitive conclusions have yet to be reached, these potential risks highlight the importance of careful fluoride management and have fueled the search for safer alternatives like nano hydroxyapatite.

The Appeal of Nano Hydroxyapatite


Unlike fluoride, nano hydroxyapatite is non-toxic and poses no risk of fluorosis or other fluoride-related health issues. This makes it particularly appealing for use in children's dental products, as it eliminates the risk of accidental fluoride overconsumption. Additionally, nano hydroxyapatite's biocompatibility means it is less likely to cause allergic reactions or other adverse effects, making it suitable for almost everyone.


Caution: just as with any product you use in or on your body, you do want to ensure that the ingredients used are safe and effective. Reach out to your manufacturer to ensure that the NHA being used is of top-quality and has been tested and approved safe for human use. The NHA used in Great Oral Health products is the only form of NHA that has been tested and approved as safe and effective by the European Scientific Commission on Consumer Safety (SCCS)

Making an Informed Choice


When choosing between fluoride and nano hydroxyapatite, the decision often comes down to individual health concerns, preferences for natural products, and specific dental needs. Nano hydroxyapatite offers a compelling alternative for those who prefer a more natural approach or have concerns about fluoride's side effects. As with any health-related choice, consulting with a dental professional can provide further guidance tailored to personal dental health conditions and goals.

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Frequently Asked Questions

How To Get Rid Of Bad Breath?

Effective bad breath remedies include:

Gentle and regular scraping of the tongue

Regular oral care practices such as daily brushing and flossing

Professional deep cleanings and plaque removal

The ongoing use of oral probiotics.

How Probiotics Work To Control Bad Breath

One, the probiotics compete with the existing bad bacteria and reduce their presence by “crowding them out”

Two, the probiotics produce BLIS or “bacteriocin-like-inhibitory-substances” which is a technical way of stating that one probiotic strain (bacteria) can produce a substance that inhibits or kills off other bacteria. Three, by working to control gingivitis, gum disease and tooth decay these probiotics reduce the very sources of bacteria-generated odors in the mouth.

How Do Oral Probiotics Work to Fight Tooth Decay?

  • First, oral probiotics can break into and colonize your mouth's biofilm, replacing the "bad" bacteria with good.
  • Second, the beneficial oral probiotics compete against the bad bacteria. In effect they crowd out the "bad" bacteria by establishing themselves in the limited space of the biofilm.
  • Third, now, with a lower volume of S. Mutans, and other acid-forming bacteria, the teeth and gums are not under the constant, disintegrating attack of acids.
  • Fourth, at the same time, the oral probiotics are producing alkaline byproducts. This action not only reduces the acids but inhibits the growth of "bad" bacteria as they thrive in acidic environments.
  • Fifth, as a part of the biofilm, the oral probiotics are able to make their way into those difficult to reach deep areas of the teeth and gums. Once there they can continuously work, 24/7, to create a balanced environment that inhibits tooth decay and gum disease while promoting the healing process.

How do Oral Probiotics Help Against Gum Disease?

  • First, our oral probiotics are chosen for their ability to penetrate into and to colonize within the biofilm (plaque) and to survive in the oral environment
  • Second, these oral probiotics have the ability to successfully compete against the harmful bacteria. There are limited resources in the biofilm and with more beneficial bacteria present then fewer harmful bacteria can exist
  • Third, it is not the presence of plaque that is so much the problem, it is the acids and toxins produced by certain bacteria that lead to gum disease and tooth decay. Fewer harmful bacteria in the plaque=lowered toxins and acids
  • Fourth, our oral probiotics improve your mouth's pH balance. This has the effect of reducing acid levels and establishes a pH level that inhibits the growth of harmful bacteria
  • Fifth, unlike brushing or flossing our oral probiotics work their way into those difficult to reach "hideout" zones and so they will work “around the clock” and not just when you brush or floss

Studies have shown a clear reduction in plaque levels and gingivitis symptoms when oral probiotics were administered to patients with moderate to severe gingivitis.